Abstract: Zebrafish are the most widely used laboratory fish today. As a highly valuable and in-demand resource, standardized quality control has become an inevitable trend in the development of zebrafish research. In this review, we introduce the compilation background, pathogen selection, pathogen grading, test item selection and test methods of the group standard for “Laboratory Animal Microbiological and parasitical standards and monitoring of zebrafish”, which is the first standard in this field. The development of this standard will provide reference for the standardized breeding of specific pathogen-free zebrafish resources, further improve the quality control level of zebrafish, and enhance the ability of laboratory fish to serve scientific and technological innovation.

Key words:  laboratory animals, zebrafish, microbiological, parasitical, specific pathogen-free, group standard

摘要： 斑马鱼是应用最为广泛的实验鱼类。作为一种极具价值且科研需求极大的实验动物资源,标准化质量控制 已经成为斑马鱼研究发展的必然趋势。本文介绍了首个《实验动物 斑马鱼微生物与寄生虫等级及监测》团体标准 的编制背景、病原选择、病原等级设定、检测项目选择和检测方法。本标准的制定将为无特定病原级斑马鱼资源的 标准化繁育提供参考,提高斑马鱼的质量控制水平,进一步提升实验鱼资源服务和科技创新的能力。

关键词: 实验动物, 斑马鱼, 微生物, 寄生虫, 无特定病原, 团体标准